The female characters of Uncharted 2 will play less of a role in the Uncharted 3: Drake’s Deception. Chloe and Elena who played a large part in Among Theives won’t have nearly as much face time in Drake’s Deception. Evan Wells recently said in an interview, “they aren’t the emphasis of the story the way they were in Uncharted 2”. In Uncharted 3, the focus is going to be much more on Nathan Drake, as well as his mentor Victor “Sully” Sullivan.
As shown in the trailers, Uncharted 3: Drake’s Deception will feature a brand new villain that happens to be a lady. Katherine Marlowe is the new antagonist of the story, and not often do games go the route of female baddie. Though she does look like a mean old B!tch, who has apparently handled her fair share of knives.