How to Block in The Callisto Protocol

Here's how to block an attack from a Biophage!

by Matthew Kevin Mitchell

Are you wondering how to block in The Callisto Protocol? The Callisto Protocol features some pretty intense combat that requires you to basically hug those biophages. Learning to be within the melee range of biophages and not immediately getting your face eaten can be tricky, so you must master specific moves like melee attacks, dodging, and blocking. You may be overwhelmed at first, but don’t work. We have everything you need to know about how to block and why blocking can give you a significant advantage, which may save your life. Here is everything you need to know on how to block in The Callisto Protocol.

How to Block in The Callisto Protocol


There will be specific times that you will want to use Block over Dodge because blocking doesn’t require the precise timing that Dodging does. You can legitimately hold down the Block button for as long or as short as you need and at any point during combat. The effects will still work regardless of your timing.

Here are the steps you need to take to block an attack from an enemy:

  • Press the S key (PC) or the Left joystick back (Controller) to initiate a Block

That’s it! A single key or button press will cause your character to initiate the Block ability whenever needed. There isn’t any special requirement or timing (other than blocking before a Biophage initiates an attack, of course). Blocking an attack will cause you to take less damage and prevent you from becoming staggered or knocked down, which may save your sanity and Jacob Lee’s life.

Just like a successful Dodge will initiate the Strategic Targeting System, a successful Dodge will allow you to take advantage of your smarts in combat. Another significant advantage of using the Block ability is allowing you to knock the enemy down with a counterattack after performing a successful Block. You can perform a counterattack by performing a Melee attack using the Left Mouse button (PC), R2 button (PlayStation), or RT button (Xbox).

The Callisto Protocol is available on PC, PlayStation 4, PlayStation 5, Xbox One, and Xbox Series X|S.

- This article was updated on December 2nd, 2022